These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.
Genomic
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NG_012038.2 RefSeqGene
Range 5014..60042 Download GenBank, FASTA, Sequence Viewer (Graphics), LRG_1391
mRNA and Protein(s)
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NM_001243027.3 → NP_001229956.1 RAC-beta serine/threonine-protein kinase isoform 2
See identical proteins and their annotated locations for NP_001229956.1
Status: REVIEWED
Description Transcript Variant: This variant (2) differs in the 5′ UTR, contains an alternate splice site in the 5′ coding region, and initiates translation at a downstream AUG. This results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode isoform 2. Source sequence(s) AC118344, AK122839, AK294453, BM675176, CN351354, KC877734 UniProtKB/TrEMBL B3KP61, B4DG79 Conserved Domains (3) summary cd05595Location:94 → 416 STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2) smart00220Location:90 → 347 S_TKc; Serine/Threonine protein kinases, catalytic domain cl17171Location:1 → 49 PH-like; Pleckstrin homology-like domain
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NM_001243028.3 → NP_001229957.1 RAC-beta serine/threonine-protein kinase isoform 2
See identical proteins and their annotated locations for NP_001229957.1
Status: REVIEWED
Description Transcript Variant: This variant (3) differs in the 5′ UTR, lacks an alternate exon in the 5′ coding region, and initiates translation at a downstream AUG. This results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode isoform 2. Source sequence(s) AC118344, AK122839, AK308006, BM675176, CN351354, KC877734 UniProtKB/TrEMBL B3KP61, B4DG79 Related ENSP00000471369.1, ENST00000579047.5 Conserved Domains (3) summary cd05595Location:94 → 416 STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2) smart00220Location:90 → 347 S_TKc; Serine/Threonine protein kinases, catalytic domain cl17171Location:1 → 49 PH-like; Pleckstrin homology-like domain
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NM_001330511.1 → NP_001317440.1 RAC-beta serine/threonine-protein kinase isoform 4
Status: REVIEWED
Source sequence(s) AC118344, BC120995, KC877734 Consensus CDS CCDS82350.1 UniProtKB/TrEMBL A0A0U4CQG9 Related ENSP00000309428.6, ENST00000311278.10 Conserved Domains (2) summary cd01241Location:4 → 111 PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain cl21453Location:156 → 435 PKc_like; Protein Kinases, catalytic domain
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NM_001626.6 → NP_001617.1 RAC-beta serine/threonine-protein kinase isoform 1
See identical proteins and their annotated locations for NP_001617.1
Status: REVIEWED
Description Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Source sequence(s) AC118344, AK122839, BC040028, BC120994, BM675176, KC877734 Consensus CDS CCDS12552.1 UniProtKB/Swiss-Prot B2RBD8, P31751, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0 UniProtKB/TrEMBL A0A0U4CQG9 Related ENSP00000375892.2, ENST00000392038.7 Conserved Domains (2) summary cd05595Location:156 → 478 STKc_PKB_beta; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B beta (also called Akt2) cd01241Location:4 → 111 PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
